A 4-generation pedigree chart showing inheritance of a pathogenic CTNNA1 variant. Chart should include a deceased great-grandfather with an unknown cancer and no genetic testing, a paternal grandfather deceased at 57 years with gastric cancer diagnosed in his 50s and no genetic testing, an unaffected paternal grandmother, a deceased paternal aunt/uncle who died in childhood, a living paternal aunt with Hodgkin's lymphoma who is negative for CTNNA1, that paternal aunt's living child (unknown if male or female), a living paternal uncle who is 61 years of age with prophylactic total gastrectomy at 60 years of age negative for in situ neoplasia (positive for CTNNA1), that paternal uncle's living daughter (who is positive for CTNNA1), a deceased father who died at 48 years of age of diffuse gastric cancer diagnosed at 47 years of age, an unaffected mother, and the affected patient who is now 19 years of age s/p total gastrectomy and is CTNNA1 positive and diagnosed with gastric cancer at the age of 17
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Browse 1014 real creationsPedigree Chart
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a big pedigree char
a big pedigree chart x linked dominant
a big pedigree chart x linked recessive
a big pedigree chart autosomal dominant
a big pedigree chart autosomal recessive
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Create a three-generation pedigree demonstrating autosomal recessive inheritance of Spinal Muscular Atrophy Type II (SMA2) caused by mutations in the SMN1 gene. Use standard pedigree symbols: squares for males, circles for females, filled symbols for affected individuals, half-filled symbols for unaffected carriers, and unfilled symbols for unaffected non-carriers. Label each individual by generation and number (I-1, I-2, II-1, etc.) and include the genotype below each individual. Use A for a normal SMN1 allele and a for a disease-causing allele, so affected individuals are aa, carriers are Aa, and unaffected non-carriers are AA. Include at least three offspring in Generation II and at least three offspring in Generation III. Have two unaffected carrier parents (Aa × Aa) in Generation II produce an affected child (aa) in Generation III. Include both males and females in the pedigree. Identify one affected individual in Generation III as the proband using an arrow. Make all individuals living so no deceased symbols are necessary. Title the pedigree “Autosomal Recessive Inheritance of Spinal Muscular Atrophy Type II (SMA2).” Include a legend explaining the symbols and genotypes.
A three-generation pedigree chart showing autosomal dominant inheritance of ADPKD, with the grandmother affected, two carrier children, and one affected grandchild
A three-generation pedigree chart showing autosomal dominant inheritance of Huntington disease, with the grandfather affected, two carrier children, and one affected grandchild
A pedigree chart for an autosomal dominant condition showing vertical transmission across four generations with one unaffected skip generation
An X-linked recessive pedigree for color blindness showing a carrier mother, an unaffected father, two affected sons, and one carrier daughter. have 99 generations
An X-linked recessive pedigree for color blindness showing a carrier mother, an unaffected father, two affected sons, and one carrier daughter. have 100 generations
An X-linked recessive pedigree for color blindness showing a carrier mother, an unaffected father, two affected sons, and one carrier daughter. have 15 generations
An X-linked recessive pedigree for color blindness showing a carrier mother, an unaffected father, two affected sons, and one carrier daughter
make a pedigree drawing of an autosomal recessive inheritance of sickle cell anaemia with 1 grandfather affected, 2 children becoming carriers and a 1 affected child. 3 genrations. DO NOT LABEL PROBAND
make a pedigree drawing of an autosomal recessive inheritance of sickle cell anaemia with 1 grandfather affected, 2 children becoming carriers and a 1 affected child. DO NOT LABEL PROBAND
make a pedigree drawing of an autosomal recessive inheritance of sickle cell anaemia with 1 grandfather affected, 2 children becoming carriers and a 1 affected child
A three-generation pedigree chart showing autosomal dominant inheritance of sickle cell disease, with the grandfather affected, two carrier children, and one affected grandchild
A three‑generation pedigree chart showing autosomal dominant inheritance of widow’s peak, with two affected grandparents, one affected child, one unaffected child, and cousins showing a full range of dominant, heterozygous, and unaffected phenotypes.
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